Inotropic agents and calcium channel blockers in PAH

Aromatorio, G. J., Uretsky, B. F. and Reddy, P. S. (1985) Hypotension and sinus arrest with nifedipine in pulmonary hypertension. Chest, 87, 265-267.

Barst, R. J. (2000) Role of atrial septostomy in the treatment of pulmonary vascular disease. Thorax, 55, 95-96.

Batra, A. K., Segall, P. H. and Ahmed, T. (1985) Pulmonary edema with nifedipine in primary pulmonary hypertension. Respiration, 47, 161-163.

Brown, S. E., Pakron, F. J., Milne, N., et al. (1984) Effects of digoxin on exercise capacity and right ventricular function during exercise in chronic airflow obstruction. Chest, 85, 187-191.

Chaouat, A., Kessler, R. and Weitzenblum, E. (1996) Pulmonary oedema and pleural effusion in two patients with primary pulmonary hypertension treated with calcium channel blockers. Heart, 75, 383.

Clarke, W. R., Horn, J. R., Kawabori, I., et al. (1993) Potentially serious drug interactions secondary to high-dose diltiazem used in the treatment of pulmonary hypertension. Pharmacotherapy, 13, 402-405.

Delcroix, M., Lejeune, P., Ewalenko, P., et al. (1995) Effects of inotropic agents on right ventriculo-vascular coupling in canine embolism. Eur Respir J, 8, 467S.

Farber, H. W., Karlinsky, J. B. and Faling, L. J. (1983) Fatal outcome following nifedipine for pulmonary hypertension. Chest, 83, 708-709.

Hoeper, M. M., Olschewski, H., Ghofrani, H. A., et al. (2000) A comparison of the acute hemodynamic effects of inhaled nitric oxide and aerosolized iloprost in primary pulmonary hypertension. German PPH study group. J Am Coll Cardiol, 35, 176-182.

Mathur, P. N., Powles, P., Pugsley, S. O., et al. (1981) Effect of digoxin on right ventricular function in severe chronic airflow obstruction. A controlled clinical trial. Ann Intern Med, 95, 283-288.

Morgan, J. M., McCormack, D. G., Griffiths, M. J., et al. (1991) Adenosine as a vasodilator in primary pulmonary hypertension. Circulation, 84, 1145-1149.

Olschewski, H., Walmrath, D., Schermuly, R., et al. (1996) Aerosolized prostacyclin and iloprost in severe pulmonary hypertension. Ann Intern Med, 124, 820-824.

Packer, M., Medina, N. and Yushak, M. (1984) Adverse hemodynamic and clinical effects of calcium channel blockade in pulmonary hypertension secondary to obliterative pulmonary vascular disease. J Am Coll Cardiol, 4, 890-901.

Partanen, J., Nieminen, M. S. and Luomanmaki, K. (1993) Death in a patient with primary pulmonary hypertension after 20 mg of nifedipine. N Engl J Med, 329, 812; discussion 812-813.

Prigogine, T., Waterlot, Y., Gottignies, P., et al. (1991) Acute nonhemodynamic pulmonary edema with nifedipine in primary pulmonary hypertension. Chest, 100, 563-564.

Rich, S. and Brundage, B. H. (1987) High-dose calcium channel-blocking therapy for primary pulmonary hypertension: evidence for long-term reduction in pulmonary arterial pressure and regression of right ventricular hypertrophy. Circulation, 76, 135-141.

Rich, S., Ganz, R. and Levy, P. S. (1983) Comparative actions of hydralazine, nifedipine and amrinone in primary pulmonary hypertension. Am J Cardiol, 52, 1104-1107.

Rich, S. and Kaufmann, E. (1991) High dose titration of calcium channel blocking agents for primary pulmonary hypertension: guidelines for short-term drug testing. J Am Coll Cardiol, 18, 1323-1327

Rich, S., Kaufmann, E. and Levy, P. S. (1992) The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. N Engl J Med, 327, 76-81.

Rich, S., Seidlitz, M., Dodin, E., et al. (1998) The short-term effects of digoxin in patients with right ventricular dysfunction from pulmonary hypertension. Chest, 114, 787-792.

Rubin, L. J., Groves, B. M., Reeves, J. T., et al. (1982) Prostacyclin-induced acute pulmonary vasodilation in primary pulmonary hypertension. Circulation, 66, 334-338.

Rubin, L. J., Nicod, P., Hillis, L. D., et al. (1983) Treatment of primary pulmonary hypertension with nifedipine. A hemodynamic and scintigraphic evaluation. Ann Intern Med, 99, 433-438.

Sitbon, O., Humbert, M., Jagot, J. L., et al. (1998) Inhaled nitric oxide as a screening agent for safely identifying responders to oral calcium-channel blockers in primary pulmonary hypertension. Eur Respir J, 12, 265-270.

Weir, E. K., Rubin, L. J., Ayres, S. M., et al. (1989) The acute administration of vasodilators in primary pulmonary hypertension. Experience from the National Institutes of Health Registry on Primary Pulmonary Hypertension. Am Rev Respir Dis, 140, 1623-1630.

Wiedermann, H. P. and Matthay, R. A. (1989) The management of acute and chronic cor pulmonale. In: Heart-lung interactions in health and disease, Vol. 42 (Eds, Scharf, S. M. and Cassidy, S. S.) Marcel Dekker, Inc., New York, Basel, pp. 915-981.

Aromatorio, G. J., Uretsky, B. F. and Reddy, P. S. (1985) Hypotension and sinus arrest with nifedipine in pulmonary hypertension. Chest, 87, 265-267.

Barst, R. J. (2000) Role of atrial septostomy in the treatment of pulmonary vascular disease. Thorax, 55, 95-96.

Batra, A. K., Segall, P. H. and Ahmed, T. (1985) Pulmonary edema with nifedipine in primary pulmonary hypertension. Respiration, 47, 161-163.

Brown, S. E., Pakron, F. J., Milne, N., et al. (1984) Effects of digoxin on exercise capacity and right ventricular function during exercise in chronic airflow obstruction. Chest, 85, 187-191.

Chaouat, A., Kessler, R. and Weitzenblum, E. (1996) Pulmonary oedema and pleural effusion in two patients with primary pulmonary hypertension treated with calcium channel blockers. Heart, 75, 383.

Clarke, W. R., Horn, J. R., Kawabori, I., et al. (1993) Potentially serious drug interactions secondary to high-dose diltiazem used in the treatment of pulmonary hypertension. Pharmacotherapy, 13, 402-405.

Delcroix, M., Lejeune, P., Ewalenko, P., et al. (1995) Effects of inotropic agents on right ventriculo-vascular coupling in canine embolism. Eur Respir J, 8, 467S.

Farber, H. W., Karlinsky, J. B. and Faling, L. J. (1983) Fatal outcome following nifedipine for pulmonary hypertension. Chest, 83, 708-709.

Hoeper, M. M., Olschewski, H., Ghofrani, H. A., et al. (2000) A comparison of the acute hemodynamic effects of inhaled nitric oxide and aerosolized iloprost in primary pulmonary hypertension. German PPH study group. J Am Coll Cardiol, 35, 176-182.

Mathur, P. N., Powles, P., Pugsley, S. O., et al. (1981) Effect of digoxin on right ventricular function in severe chronic airflow obstruction. A controlled clinical trial. Ann Intern Med, 95, 283-288.

Morgan, J. M., McCormack, D. G., Griffiths, M. J., et al. (1991) Adenosine as a vasodilator in primary pulmonary hypertension. Circulation, 84, 1145-1149.

Olschewski, H., Walmrath, D., Schermuly, R., et al. (1996) Aerosolized prostacyclin and iloprost in severe pulmonary hypertension. Ann Intern Med, 124, 820-824.

Packer, M., Medina, N. and Yushak, M. (1984) Adverse hemodynamic and clinical effects of calcium channel blockade in pulmonary hypertension secondary to obliterative pulmonary vascular disease. J Am Coll Cardiol, 4, 890-901.

Partanen, J., Nieminen, M. S. and Luomanmaki, K. (1993) Death in a patient with primary pulmonary hypertension after 20 mg of nifedipine. N Engl J Med, 329, 812; discussion 812-813.

Prigogine, T., Waterlot, Y., Gottignies, P., et al. (1991) Acute nonhemodynamic pulmonary edema with nifedipine in primary pulmonary hypertension. Chest, 100, 563-564.

Rich, S. and Brundage, B. H. (1987) High-dose calcium channel-blocking therapy for primary pulmonary hypertension: evidence for long-term reduction in pulmonary arterial pressure and regression of right ventricular hypertrophy. Circulation, 76, 135-141.

Rich, S., Ganz, R. and Levy, P. S. (1983) Comparative actions of hydralazine, nifedipine and amrinone in primary pulmonary hypertension. Am J Cardiol, 52, 1104-1107.

Rich, S. and Kaufmann, E. (1991) High dose titration of calcium channel blocking agents for primary pulmonary hypertension: guidelines for short-term drug testing. J Am Coll Cardiol, 18, 1323-1327.

Rich, S., Kaufmann, E. and Levy, P. S. (1992) The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. N Engl J Med, 327, 76-81.

Rich, S., Seidlitz, M., Dodin, E., et al. (1998) The short-term effects of digoxin in patients with right ventricular dysfunction from pulmonary hypertension. Chest, 114, 787-792.

Rubin, L. J., Groves, B. M., Reeves, J. T., et al. (1982) Prostacyclin-induced acute pulmonary vasodilation in primary pulmonary hypertension. Circulation, 66, 334-338.

Rubin, L. J., Nicod, P., Hillis, L. D., et al. (1983) Treatment of primary pulmonary hypertension with nifedipine. A hemodynamic and scintigraphic evaluation. Ann Intern Med, 99, 433-438.

Sitbon, O., Humbert, M., Jagot, J. L., et al. (1998) Inhaled nitric oxide as a screening agent for safely identifying responders to oral calcium-channel blockers in primary pulmonary hypertension. Eur Respir J, 12, 265-270.

Weir, E. K., Rubin, L. J., Ayres, S. M., et al. (1989) The acute administration of vasodilators in primary pulmonary hypertension. Experience from the National Institutes of Health Registry on Primary Pulmonary Hypertension. Am Rev Respir Dis, 140, 1623-1630.

Wiedermann, H. P. and Matthay, R. A. (1989) The management of acute and chronic cor pulmonale. In: Heart-lung interactions in health and disease, Vol. 42 (Eds, Scharf, S. M. and Cassidy, S. S.) Marcel Dekker, Inc., New York, Basel, pp. 915-981.